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The "Big Book" is referring to the book of Alcoholics Anonymous. Regardless of your substance of choice, this book is an outline on how to get sober and stay sober through being relieved of the obsession to use. The "Big Book" has a program with in it that is applicable to life for anyone who is willing to do the work. Many people in 12-step meetings, such as, Alcoholics Anonymous, Crystal Meth Anonymous, Cocaine Anonymous and Heroine Anonymous use this book to get sober.