Mescaline is a psychedelic alkaloid that naturally occurs in the Peyote cactus, native to Mexico and Texas, and the San Pedro Cactus, native to the Andes Mountains of South America. Like other psychedelic drugs, using Mescaline alters your perception of reality and induces hallucinations. It can distort your vision, heighten the senses, and confuse your sense of time and space. Traditionally it has been used by natives and shamans to enhance spiritual experiences or rituals and as natural medicine.
Other drugs that are similar to Mescaline, producing the classical psychedelic effects, are LSD, Psilocybin Mushrooms, and DMT. Mescaline also can have some entactogenic effects, emotional and social effects that is, which are more commonly associate with drugs like MDMA. While tolerance to Mescaline can develop quickly, there is not much research or reporting on trends of physical or psychological dependence. There are some dangers to using Mescaline, though, the most severe being a risk of sustained psychotic states similar to schizophrenia.
The effects of Mescaline typically persist for 8 to 12 hours, but may vary depending on how the drug is prepared and consumed, as well as the size of dose. Physical effects include a euphoric sensation or a warm glow about the body and sometimes electric tingling moving up and down the body.
Mescaline can be stimulating and the user may feel the desire to be physically active, running around or dancing. Nausea is also experienced, usually shortly after taking the drug. Seizures have rarely been observed in users of Mescaline, but it is believed that someone who is predisposed to seizures may be more likely to have one if using this drug.
The psychological effects of Mescaline can be extreme and may possibly encourage a psychologic addiction or abuse of the drug. If you believe a loved one is abusing Mescaline or another psychedelic drug, there are some things to look out for that may be indicators. An individual who is abusing Mescaline may display shift in their personality, behaving more erratically than is usual or expressing beliefs that seem counter the person’s previous ideology. Your loved one could become delusional, develop paranoia or conspiracies that are unrealistic and possibly lose touch with common reality.
Enhanced senses have been reported with Mescaline use, as well as perceiving colors and visual patterns to be enhanced. Mescaline can distort the vision, so that things appear to be breathing, melting or pulsing, and geometric structures are more distinct. A person can experience visual hallucinations, as well as internal hallucinations which are imagined.
Cognitive effects can include euphoria and a sense of well-being or connectedness, heightened creativity, delusional thoughts, intense empathy and social urges, as well as the inhibition of memory formation. Mescaline can also induce synesthesia which is a mixing of the senses, such as hearing colors or seeing music. A warped or irregular sense of time is common to experience, including time warp and confusion about what just happened.
Mescaline use can have adverse psychological effects, often causing fear and anxiety with an elevated heart rate. While we understand that Mescaline interacts with the catecholamine and serotonin neurotransmitters, it is not known why or how it produces the psychedelic experiences that it does. Long-term use of Mescaline can contribute to a person developing depression. It is also possible to randomly experience psychedelic effects or flashbacks from the experience after the trip has ended.
As stated before, a person may even experience psychosis that resembles Schizophrenia and can include delusional thoughts or behaviors. This can persist for a long time or possibly be permanent and is much more likely in individuals who are predisposed to mental illness or have previously been diagnosed with psychiatric disorders.
Tolerance to Mescaline is developed very quickly in the body, although sensitivity is restored after a week or two without using the drug. This includes cross tolerance, meaning that the effects of other psychedelic drugs, such as LSD or Psilocybin, will also be dulled if a tolerance to Mescaline is built up in the system. This tolerance does not coincide with a physical dependence, however, and ceasing to take Mescaline will not result in any physical withdrawal symptoms. Because of this, there is not a lot of evidence of the possibility of physical addiction.
While it is not proven to be deadly, even in high doses, Mescaline can be dangerous in combination with certain drugs. People who develop addictions to substances will often try new drugs or combinations of drugs in order to enhance the effects further or intensify the high. This could be deadly. If you believe a loved one is addicted to or abusing Mescaline, or any other drug, you should seek professional help. There are many resources and services available to those suffering from addiction.