Side Effects of Drug & Alcohol Detox: What to Expect and How to Prepare

   May. 25, 2018
   4 minute read
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Last Edited: July 18, 2025
Author
Andrew Lancaster, LPC, MAC
Clinically Reviewed
Mark Frey, LPCC, LICDC, NCC
All of the information on this page has been reviewed and certified by an addiction professional.

“The road to recovery will not always be easy, but it is always worth it.”
— Demi Lovato

Detox is the first step toward getting clean and sober—but it’s not without risk. Many people don’t realize how serious the side effects of drug and alcohol detox can be. From painful cravings to life-threatening seizures, detox can be overwhelming—especially without medical help.

Quitting drugs or alcohol suddenly can trigger what doctors call detox withdrawal symptoms. These can range from sweating and nausea to intense anxiety, hallucinations, or even heart problems. In fact, alcohol withdrawal alone kills hundreds of people every year in the U.S. if not treated properly.

The truth? Detox can save your life—but only if done safely.

Why Detox Is Necessary, But Not Easy

When you use drugs or alcohol over time, your body gets used to them. Your brain’s chemistry changes to adapt. So when you stop, your body reacts—sometimes in extreme and dangerous ways. That reaction is what we call withdrawal.

It’s not just “feeling sick” or having the shakes. Some withdrawal symptoms can be medical emergencies.

Common Detox Withdrawal Symptoms to Watch Out For

Here’s what you might experience during detox:

  • Headaches
  • Nausea and vomiting
  • Sweating
  • Shaking or tremors
  • Muscle aches
  • Anxiety or panic attacks
  • Insomnia
  • Depression or mood swings
  • Seizures
  • Hallucinations
  • Heart palpitations
  • Fever or chills

The symptoms you face will depend on what substances you’ve been using, how long, and how much. Alcohol, opioids, benzodiazepines, and stimulants like cocaine or meth all come with different risks and timelines.

Alcohol Detox: A Closer Look at the Risks

Alcohol detox is one of the most dangerous types. If you’ve been drinking heavily for a long time, you could face delirium tremens (DTs)—a severe condition that includes confusion, hallucinations, high fever, and even death if untreated.

According to the National Institute on Alcohol Abuse and Alcoholism (NIAAA), about 50% of people with alcohol dependence will experience withdrawal, and 3–5% will develop DTs.

That’s why medical supervision is so important.

Opioid Detox: Painful but Rarely Deadly

Detoxing from opioids like heroin or prescription painkillers is extremely uncomfortable. You may feel like you have the flu times ten: body aches, runny nose, chills, and vomiting. But unlike alcohol, opioid withdrawal is rarely fatal.

Still, the discomfort is so intense that many people relapse just to stop the pain.

Benzo Detox: Silent and Dangerous

Benzodiazepines (like Xanax, Valium, or Ativan) can be just as dangerous as alcohol. Stopping cold turkey may lead to seizures, hallucinations, or heart problems. These symptoms can come on fast and must be managed in a hospital or detox center.

Stimulant Detox: The Crash Is Real

Drugs like cocaine, meth, or ADHD medications don’t cause severe physical symptoms, but the mental symptoms can be crushing. You may feel:

What’s the Timeline for Withdrawal Symptoms?

Here’s a general idea of what to expect:

SubstanceSymptoms BeginPeakDuration
Alcohol6–12 hours24–72 hours4–7 days
Heroin6–24 hours2–3 days5–10 days
Benzos1–4 days2–7 daysWeeks or more
Stimulants24–72 hours4–5 days1–2 weeks (psych issues)

How to Prepare for Detox

1. Talk to a Doctor or Addiction Specialist

Never attempt detox alone. A medical team can help you detox safely, provide medications, and monitor your vitals 24/7.

2. Consider Inpatient Detox

Inpatient programs provide structure, safety, and support. They also offer a smooth transition into rehab or therapy after detox.

3. Plan Ahead

Get time off work, arrange child care, and make sure someone knows where you are. Detox can be unpredictable.

4. Pack for Comfort

Bring loose clothes, books, music, or anything that brings you peace.

Medical Detox: Why It Could Save Your Life

Medical detox means you’ll be monitored by nurses and doctors. They can give you medications to ease symptoms and prevent serious complications. Some common medications include:

  • Benzodiazepines (for alcohol or sedative withdrawal)
  • Buprenorphine or methadone (for opioid withdrawal)
  • Anti-nausea or anti-seizure meds
  • IV fluids and vitamins

You’re not weak for needing help—you’re smart for doing it safely.

Hope Beyond Detox: The Start of Recovery

Detox is only the first step. Real recovery comes after, through therapy, peer support, lifestyle changes, and time. But here’s the good news: Thousands of people do it every day.

Whether you choose inpatient rehab, outpatient care, 12-step meetings, or individual therapy, what matters most is not doing it alone.

Recovery is possible. Detox is just the beginning of your new life.

The side effects of drug and alcohol detox are real—and sometimes dangerous. But with the right help, you can get through it safely. Don’t let fear stop you from taking that first step. You’re stronger than you think.

“It does not matter how slowly you go, as long as you do not stop.”
– Confucius

Frequently Asked Questions
What are the most common side effects of drug and alcohol detox?
The most common side effects include anxiety, nausea, sweating, shaking, insomnia, headaches, and intense cravings. In severe cases, withdrawal can lead to seizures, hallucinations, and heart problems—especially during alcohol or benzodiazepine detox.
How long do detox withdrawal symptoms last?
Detox withdrawal symptoms can last anywhere from a few days to several weeks. Alcohol and opioid symptoms typically peak within 3 days, while benzodiazepine and stimulant withdrawal may last longer. Each person’s timeline depends on their drug history and overall health.
Is it safe to detox from alcohol and drugs at home?
Detoxing at home can be dangerous, especially for heavy users. Without medical help, you risk severe symptoms like seizures or delirium tremens. A supervised medical detox is the safest option to manage withdrawal and avoid complications.
What medications are used to manage detox withdrawal symptoms?
Doctors may use medications like benzodiazepines for alcohol withdrawal, methadone or buprenorphine for opioid detox, and anti-nausea or seizure medications to ease discomfort. These meds reduce risks and make detox more manageable.
Can detox help with long-term addiction recovery?
Yes. Detox is the first step in recovery, helping to clear the body of harmful substances. While it doesn’t treat addiction itself, detox sets the stage for further treatment like therapy, inpatient rehab, or outpatient programs that support lasting recovery.
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