Fentanyl and Pregnancy

Last Edited: April 15, 2024
Author
Patricia Howard, LMFT, CADC
Clinically Reviewed
Andrew Lancaster, LPC, MAC
All of the information on this page has been reviewed and certified by an addiction professional.

Fentanyl addiction during pregnancy is a critical public health concern with profound implications for both maternal and neonatal health. As one of the most potent opioids, fentanyl poses significant risks not only to the user but also to the developing fetus. Understanding these risks and the necessary interventions can help mitigate the adverse outcomes associated with opioid use during pregnancy.

The Scope of the Problem

Fentanyl is up to 100 times more potent than morphine and 50 times more potent than heroin. Its high potency increases the risk of overdose and addiction. According to the Centers for Disease Control and Prevention (CDC), opioid use during pregnancy has been steadily increasing, with opioid-related disorders in pregnant women more than quadrupling from 1999 to 2014. This trend underscores the growing need for targeted interventions and specialized care for this vulnerable population.

Risks Associated with Fentanyl Use During Pregnancy

1. Neonatal Abstinence Syndrome (NAS): One of the most immediate and visible effects of fentanyl addiction during pregnancy is Neonatal Abstinence Syndrome (NAS). NAS occurs when a baby withdraws from certain drugs he or she was exposed to in the womb before birth. Babies born to mothers who use fentanyl may experience withdrawal symptoms such as tremors, irritability, sleep problems, high-pitched crying, tight muscle tone, hyperactive reflexes, seizures, yawning, sneezing, poor feeding and suck, vomiting, and diarrhea. The incidence of NAS has increased in parallel with the rise in opioid use, with hospitals across the U.S. reporting a significant uptick in cases.

2. Miscarriage and Preterm Labor: Fentanyl use during pregnancy increases the risk of miscarriage and preterm labor. Opioids can interfere with the normal progression of pregnancy, potentially leading to premature birth, which itself is associated with a host of developmental issues for the newborn.

3. Low Birth Weight: Babies born to mothers addicted to fentanyl are more likely to have low birth weight, defined as weighing less than 5 pounds, 8 ounces. Low birth weight is a concern because it is linked to several infant and childhood complications, including infections, developmental delays, and even infant mortality.

4. Congenital Disabilities: While research is still ongoing, preliminary studies suggest an association between opioid use during pregnancy and congenital disabilities. These may include heart defects, hydrocephaly, and gastroschisis, where the baby’s intestines are outside the body.

5. Maternal Health Complications: Pregnant women who use fentanyl face increased health risks themselves, including heightened chances of infections, anemia, and heart conditions. These health issues can complicate pregnancy and childbirth, increasing the likelihood of complications during delivery.

Treatment and Management

Managing fentanyl addiction during pregnancy requires a comprehensive approach that includes both the mother and the developing fetus. Treatment options include:

1. Medication-Assisted Treatment (MAT): MAT using methadone or buprenorphine is considered safe and effective for treating opioid use disorders in pregnant women. These medications help reduce cravings and withdrawal symptoms and have been shown to improve pregnancy outcomes.

2. Prenatal Care: Integrating substance use treatment with prenatal care is crucial. Regular check-ups allow healthcare providers to monitor the pregnancy and manage any complications arising from opioid use effectively.

3. Counseling and Support: Behavioral therapies and support groups can provide emotional support and practical advice for managing addiction during pregnancy. These resources are vital for helping expectant mothers navigate the challenges of sobriety and parenting.

4. Postnatal Care: After delivery, both the mother and the infant should receive comprehensive care. Infants may require treatment for NAS, while mothers may need ongoing support to maintain sobriety and care for their newborn.

Frequently Asked Questions

Q: Can fentanyl use during pregnancy affect fetal development?

A: Yes, fentanyl use during pregnancy can significantly affect fetal development. Risks include premature birth, low birth weight, and withdrawal symptoms in the newborn, known as Neonatal Abstinence Syndrome (NAS). There is also an increased risk of congenital disabilities, though specific risks can vary based on usage patterns and overall maternal health.

Q: What is Neonatal Abstinence Syndrome (NAS), and how is it treated?

A: Neonatal Abstinence Syndrome (NAS) is a condition that occurs when a baby withdraws from certain drugs they were exposed to in the womb before birth. Babies exposed to fentanyl during pregnancy can experience NAS, which may manifest as tremors, excessive crying, feeding difficulties, and seizures. Treatment includes medical care in a neonatal intensive care unit (NICU), where babies can receive fluids and sometimes medications to manage withdrawal symptoms effectively.

Q: Is it safe to stop using fentanyl abruptly during pregnancy?

A: No, it is not safe to stop using fentanyl abruptly during pregnancy due to the risk of severe withdrawal symptoms that can stress the fetus and lead to complications such as miscarriage or preterm labor. Pregnant women who wish to stop using fentanyl should do so under the guidance of a healthcare provider who can offer medication-assisted treatment (MAT) to manage withdrawal symptoms safely.

A: The recommended treatments for managing fentanyl addiction during pregnancy include Medication-Assisted Treatment (MAT) with medications like methadone or buprenorphine, which are safe for use during pregnancy. These treatments help stabilize the mother’s condition, reduce opioid cravings, and minimize withdrawal symptoms. Alongside MAT, counseling and prenatal care are crucial to monitor the pregnancy and address any complications.

Q: How can fentanyl use during pregnancy affect the mother’s health?

A: Fentanyl use during pregnancy can exacerbate typical pregnancy complications and introduce new risks. Pregnant women using fentanyl are at a higher risk for anemia, infections, heart conditions, and poor nutritional health. These conditions can complicate pregnancy and childbirth, increasing the likelihood of interventions during delivery and postnatal complications.

Source