Gabapentin Withdrawal Symptoms, Signs & Side Effects

Gabapentin, originally developed as an antiepileptic drug, has been increasingly prescribed for pain, especially neuropathic pain, and certain psychiatric disorders. Its efficacy for various conditions is well-documented. However, as with many medications, there are potential side effects and withdrawal symptoms associated with its discontinuation, particularly if done abruptly or without medical supervision. This article dives into understanding gabapentin withdrawal, its signs, symptoms, and associated side effects.

Understanding Gabapentin

Before delving into withdrawal, it’s vital to have a brief overview of gabapentin. Gabapentin belongs to a class of drugs known as anticonvulsants or antiepileptics and is sold under several brand names, the most common being Neurontin. Over the years, aside from treating seizures, it has been utilized to treat chronic pain, restless leg syndrome, and even mood disorders.

Gabapentin Withdrawal Symptoms

The cessation of gabapentin, especially if done suddenly, can result in a host of withdrawal symptoms. Similar to that of alcohol withdrawal. These symptoms arise because the body becomes accustomed to the presence of the drug and, in its absence, reacts adversely.

Common withdrawal symptoms include:

  • Anxiety: Individuals might experience heightened levels of anxiety, nervousness, or restlessness.
  • Insomnia: Difficulties in falling or staying asleep can manifest after discontinuing the drug.
  • Nausea: Some people may feel nauseated or might even vomit.
  • Sweating: Excessive perspiration, especially during sleep, is a frequent symptom.
  • Pain: Pain can return or even intensify after stopping the medication.
  • Headaches: Migraines or regular headaches may occur.
  • Confusion: Some individuals report feeling disoriented or confused.
  • Depression: Mood swings or feelings of profound sadness can arise.
  • Seizures: In rare instances, especially in those originally taking gabapentin for seizure control, seizures can recur.

Signs of Gabapentin Withdrawal

Recognizing withdrawal is the first step to address it. If someone is showing the following signs after reducing or stopping their gabapentin dosage, they might be experiencing withdrawal:

  • Rapid heart rate or palpitations
  • Tremors or shakiness
  • Agitation or increased irritability
  • Rapid mood changes
  • Fatigue or extreme drowsiness

Side Effects of Gabapentin

Outside of withdrawal, gabapentin has its potential side effects, which might be confused with withdrawal symptoms. Some of these side effects include:

  • Dizziness or lightheadedness
  • Fatigue
  • Dry mouth
  • Changes in vision
  • Weight gain

Managing Gabapentin Withdrawal

Managing gabapentin withdrawal effectively requires medical oversight. If you or someone you know is considering reducing or discontinuing gabapentin:

Tapering Off: It’s crucial not to stop gabapentin suddenly. A healthcare professional can provide a safe tapering schedule.

Symptom Management: Certain symptoms, like nausea or headache, can be managed with over-the-counter medications, but always consult with a healthcare provider first.

Stay Hydrated: Drinking water can alleviate some of the withdrawal symptoms.

Seek Support: Talking to others, joining a support group, or undergoing therapy can help manage the psychological aspects of withdrawal.

Gabapentin Withdrawal Symptoms, Signs & Side Effects

Gabapentin, while beneficial for many conditions, should be taken and discontinued with caution. Recognizing and managing its withdrawal symptoms ensures a smoother transition off the medication. It’s essential always to consult with a medical professional before making changes to any medication regimen.


Always remember that individual experiences with medications can vary. The mentioned symptoms and effects might not encompass every individual’s experience, and thus, personal observation and medical guidance are paramount. Call now (866) 578-7471.

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